Simonne Raymonde Marie Weber was born on October 28, 1930, in Ancerville, France. Her father was a mechanic, and her mother worked as a laborer. When Simone was four years old, her parents separated. Her mother was sick and took care of two children, while Simone and her sister Madeleine stayed with their father.

Simone and her sister did not have diplomas and chose to leave their family home. They married the Thuot brothers. Simone had five children in total: three girls and two boys. Eventually, she faced many challenges in her marriage. She left her husband because of his alcoholism and took on odd jobs to support her children. Sadly, two of her children died when they were quite young. This deep loss affected Simone's mental health, leading her to experience mythomania and paranoia.

In 1977, Simone responded to an advertisement looking for a companion for Marcel Fixard. He was in need of a helper, but Simone did not fit the profile he was seeking. Despite this, she pretended to be a retired philosophy professor who was divorced and without children. Simone got the job and later organized a fake marriage to Marcel Fixard. 

Simone Weber became a suspect after Bernard Hettier went missing on June 22, 1985. He had been seen with her before his disappearance. Witnesses reported that they saw her waiting in her car outside his home and threatening him with a rifle. Two weeks later, Hettier's daughter, Patricia, placed a missing persons notice in the newspaper. Investigators quickly turned their attention to Simone.

The investigation revealed multiple clues suggesting Simone’s involvement. A sick note, which was allegedly sent by Hettier to his employer, was actually prescribed to another person. The police found numerous rubber stamps at Simone’s house, which could create fake medical documents. Neighbors reported hearing loud noises from her home the night before Hettier's disappearance, like she was cleaning or vacuuming.

On June 21, the day before Hettier went missing, Simone rented a concrete grinder, which was later found in her car with blood and human remains on it. Hettier's vehicle was also missing. Surveillance of conversations between Simone and her sister revealed that they used code words to discuss their situation, raising suspicion further.

The investigation continued for months. During a search of Simone’s sister's home, police found Hettier's vehicle registration and documents. A fisherman discovered a human torso in a suitcase in a river on September 15, 1985. The suitcase matched descriptions from Patricia Hettier, leading to the conclusion that the remains belonged to Bernard Hettier.

On November 8, 1985, Simone and her sister were arrested. During the investigation, it was concluded that physical evidence pointed to Simone Weber as the likely perpetrator of Hettier's murder. Investigators believe that Simone shot Hettier and used the grinder to dismember him.

Simone’s past came to light once the investigation into Hettier's disappearance began. She was connected to the suspicious death of her former husband, Marcel Fixard. After a false marriage to him, he died under mysterious circumstances shortly after their wedding. She had created a fake will to inherit from Fixard, which further added to the suspicions against her.

Eventually, the trial for Simone Weber took place from January to February 1991. During the trial, Simone was charged with the dismemberment of Hettier's body. She faced many outbursts in court and was known to insult witnesses. On February 28, 1991, she was found guilty of cutting up Hettier's body but was acquitted of premeditated murder. She received a twenty-year prison sentence.

Simone Weber remained in prison for fourteen years. She was released on November 17, 1999, after serving her sentence. After her release, she lived with her sister in Cannes. In 2017, she expressed a desire to contest her conviction, maintaining her innocence to the end. Simone Weber died on April 11, 2024, at the age of 93.