Maina Ramulu was born in 1976 in Arutla village, located in the Indian state of Telangana. Coming from a modest background, Ramulu later worked as a stone-cutter, a labor-intensive trade common in the region. His early life appeared to follow a relatively ordinary path until a personal trauma in early adulthood reportedly altered the course of his psyche permanently.

At the age of 21, his family arranged a marriage for him, a common practice in rural Indian culture. However, just days after the ceremony, his wife eloped with another man, leaving him humiliated and embittered.

Between 2003 and 2009, Ramulu began his first series of murders in Hyderabad, India. He targeted single women in toddy shops, drinking with them until they were intoxicated. Once the establishments emptied, he strangled his victims using their saris and stole their valuables. He was arrested on October 14, 2009, and sentenced to life imprisonment on February 21, 2011. ​

In December 2011, while receiving treatment at a psychiatric hospital, Ramulu escaped alongside five other inmates. During this period, he murdered five more women in areas including Bowenpally, Chandanagar, and Dundigal. He was apprehended again on May 13, 2012, and returned to prison. ​

After appealing to the Telangana High Court, Ramulu was released in 2018. He then committed two additional murders in Shamirpet and Patancheru before being arrested later that year. ​

In 2020, following another successful appeal, Ramulu was released on July 31. He allegedly murdered two more women in December 2020. The first victim, an unidentified woman aged between 35 and 45, was killed on December 10 in Japta Singayapalli village. The second, Kavala Venkatamama, 50, was murdered on December 30 in Ankushapur village. CCTV footage linked Ramulu to these crimes, leading to his arrest on January 26, 2021.