Very little is known about the early life or origins of Annice. She was an enslaved Black woman living in Clay County, Missouri under the ownership of Jeremiah Prior, a white enslaver. Her exact birth year, place of birth, and background are undocumented, as was common for enslaved individuals in early 19th-century America. Annice was one of many enslaved women whose existence was recorded only in the context of servitude or legal proceedings.

What is confirmed is that she was a mother to at least two children, Billy (age 5) and Nancy (age 2). These children, like their mother, were considered property under the system of slavery. Their lives, like hers, were bound by the brutal laws of forced servitude in the Antebellum South.

Despite being enslaved, Annice was given a trial and legal representation following her arrest, which was rare but not unheard of for capital cases involving enslaved people during that period. She stands out historically as the first enslaved woman legally executed in Missouri, and her case remains one of the earliest recorded legal executions in Clay County, which was established in 1822.

On 27 July 1828, Annice was formally indicted for the murder of five enslaved children in Clay County, Missouri. The victims included her own two children, Billy and Nancy, along with Ann, Nelly, and Phebe—all enslaved and owned by the same man, Jeremiah Prior. The parentage and ages of the other three children remain undocumented.

According to the court indictment, Annice deliberately pushed the five children into a body of water that was five feet deep, where they drowned. The indictment stated that the children were "choked, suffocated and drowned, of which they instantly died." The incident likely took place at Tryst Falls, a natural area near present-day Excelsior Springs.

Despite being enslaved, Annice was afforded a jury trial and had a defense attorney, which was an unusual but not unprecedented step at the time for capital cases. She was quickly found guilty and sentenced to death. Just a month later, on 23 August 1828, she was publicly hanged in the town of Liberty, which served as the Clay County seat. The execution was carried out by Sheriff Shubael Allen.

There is some speculation that Annice may have been related to another enslaved woman of the same name, who was lynched in 1850 in Clay County for the attempted murder of her enslaver. However, no direct connection has been established beyond the shared name and location.