Anna Margaretha Zwanziger was born on August 7, 1760, in Nuremberg, which was part of the Holy Roman Empire at the time.

Anna Margaretha Zwanziger was a German serial killer who lived in the late 18th and early 19th centuries. Her crimes took place from 1801 to 1811 while she worked as a housekeeper for several judges in Germany. Zwanziger used arsenic to poison her employers. After poisoning them, she would care for them, pretending to help them recover to gain their trust and favor.

During her time as a housekeeper, Zwanziger poisoned three people and attempted to poison many others. In total, she was responsible for the deaths of four individuals, which included a baby. Her actions were deceitful and planned, leading her to commit these crimes while maintaining her role as a caregiver.

When Zwanziger was caught, she was tried for murder. The court found her guilty, and she received the death penalty. Before her execution by beheading, she expressed a belief that her execution was necessary. She stated that she likely could not stop killing if she were to be set free. Her story is remembered as one of the notable cases of serial killing in German history.